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Topical Metformin Shows Potential Benefit for Late Stage Central Centrifugal Cicatricial Alopecia

Updated: Oct 16, 2022


Black Derm Skin Experts, Black Dermatologist Directory, African American Dermatologist, Black Skin Dermatology, Skin of Color Dermatology

Black Dermatologist Directory, Black Derm Skin Experts, African American Dermatologist, Black Skin Dermatology, Skin of Color Dermatology

ARTICLE HIGHLIGHTS:


  • Given the often mild symptoms of central centrifugal cicatricial alopecia (CCCA), patient typically present at lat stages with large areas of scarring

  • Metformin is a medication typically used to treat diabetes and has been shown in animal studies to improve scaring.

  • The study demonstrated the improvement of patients with late stage CCCA using topical compounded metformin 10% after failure with traditional therapies.


COMMENTS


  • Late stage CCCA is often difficult to treat with limited therapies offering benefit.

  • Topical compounded metformin 10% is new and interesting treatment option for late stage CCCA. It should be studied in more detail to assess the mechanism of action and long term efficacy.


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